Vaccine is claimed to be a miraculous gift from the medical field to humanity. Vaccine is made by using an attenuated strain of the virus or a less harmful virus than the definite one and introduce it to human body. Body generates an immune response as soon as it recognises a foreign object entering the body. The immune response created once, always stays as a memory in immune system, hence the next time if the same foreign body (immunologically known as an antigen) is identified entered, it is eliminated out immediately.
Our very well-known COVID-19 or Corona Virus or SARS-CoV 2 virus, has created a havoc in the whole world. A vaccination for COVID-19 or Corona Virus or SARS-CoV 2 virus, is the need of the hour. Fortuitously, this year Vaccine making process has spanned a huge difference of 15-20 years of vaccine creation to about 1 year of research for development of vaccine against the Corona Virus. There are many countries that are under Phase three of Clinical Trials, although this vaccine is created from the proteins that are present on the Corona Virus which will ideally act as the antigen to create an immune response. This vaccine into the trials, but has some underlying effects on the human body, also this vaccine needs to be stored at -70 Degree Celsius & some of them require 2 doses of vaccine to be taken to generate complete immunity.
Overcoming all these factors, scientists claim that the RegaVax 2021, is going to be an extraordinary vaccine for present COVID 19 Pandemic. The new vaccine is yet in animal trails. This vaccine uses the Yellow fever causing virus as the vector, this will provide vaccination against the Yellow fever. This will also be a delightful news for the WHO’s Campaign to eradicate Yellow Fever Until 2026. The strain “YF17D” is being used now for a long time in the vaccination for Yellow Fever disease. Considering this is, it already offers a relief that it will not be a harmful strain to be used as a vaccination. It will be the World’s First Double Target Vaccine. To create this vaccine friendly strain, they genetically engineered a small virulence genetic information from the Corona Virus and inserted it into the “YF17D”. The genetically modified organism expresses the identical spike proteins as the Corona Virus. When these cells infect the human cells, it generates the same immune response, but supresses the infection as the virus isn’t COVID-19 or Corona Virus or SARS-CoV 2 virus.
The vaccine when tested on hamsters it did not produce any Lung infection but the ones that received another Vaccine showed clear signs of Lung Disease. The vaccination of Monkeys displayed an immune response and clearance of all antigens within 7 days of active vaccination. This result is quite encouraging while compared to other vaccines. Once the human Clinical trials are carried out, this vaccine may be the most preferred vaccine against COVID-19 or Corona Virus or SARS-CoV 2 virus.